Menon MEdical Diagnostics &
CardioVascular Engineering Lab
Quantitative diagnostic screening, simulation-driven medical device design and surgical planning can improve outcomes of neonatal, pediatric and adult cardiovascular procedures.
The Medical Diagnostics and Cardio-Vascular Engineering Lab.
Contact:
PI: Google Scholar Page
ResearchGate
NSF-XSEDE profile
Twitter: @themedcave
Dr. Menon is the Director of The Medical Diagnostics & Cardio-Vascular Engineering lab - The MeDCaVE - a multidisciplinary research program, innovating at the confluence of radiology, surgical practice, informatics and high performance computing. The MeDCaVE is dedicated to healthcare advancement using robust algorithmic analysis of biomedical imaging data augmented with physics-based numerical modeling of biomechanics, which is invaluable for early technical feasibility assessment studies of novel medical device technologies. Dr. Menon's research has seen primary application in the development of quantitative metrics to support time-critical decisions relating to pediatric or adult cardiovascular pathologies, which has in-turn begun to see extended application in optimization of innovative image-guided device deployment strategies for improved outcomes and quality of life after complex surgical procedures. While the focus of research has been on novel software on the frontiers of image-based surgical planning & surgical navigation software, The MeDCaVE is also home to a one-of-it's-kind experimental facility for 3D tomographic flow quantification (at Duquesne University).
Current Affiliations:
- Mathematics & Data Analytics, Carlow University, Pittsburgh, PA (USA) [Apr 2019 - ]
- BME, University of Texas at San Antonio, San Antonio, TX (USA) [Jan 2014 - ]
- BioE, University of Pittsburgh, Pittsburgh, PA (USA) [Apr 2014 - ]
Former Appointments:
- BME, Carnegie Mellon University, Pittsburgh, PA (USA) [Jan 2019 - Aug 2019]
- Heinz College, Carnegie Mellon University, Pittsburgh, PA (USA) [Aug 2018 - Aug 2019]
- BME, Duquesne University, Pittsburgh, PA (USA), Tenure-track [Aug 2015 -Aug 2018]
- ECE, Sun Yat-sen University (SYSU) - CMU Joint Institute of Engineering (JIE),
Shunde International Joint Research Institute, Guangdong (China), Associate
Professor, School of Mobile Information Engineering (SMIE), Sun Yat-sen
University, Zuhai, China.
ECE, Carnegie Mellon University (CMU), Pittsburgh, PA (USA) [June 2013 - May 2015]
ORCID : http://orcid.org/0000-0002-4249-9319 . DigitalVita (University of Pittsburgh).
Resume : www.linkedin.com/in/prahladmenon ; NCBI (NIH Biosketch).
Email :
Carlow : pgmenon@carlow.edu
Pitt : prm44@pitt.edu
UTSA : prahlad.menongopalakrishna@utsa.edu
Duquesne : menongopalakrip@duq.edu
CMU / SYSU : pgmenon@andrew.cmu.edu , menon@mail.sysu.edu.cn
Tel : +1 (412) 259-3031
View The MeDCaVE's list of peer-reviewed publications from 2013-18 by
scrolling down this page Or visit my Students Page.
3D Tomographic Particle Image Velocimetry (PIV)
The MeDCaVE's new Tomographic Particle Image Velocimetry (PIV) system opens doors for quantifying 3D+time fluid dynamics in complex cardiovascular geometries, by enabling the instantaneous measurement of all three velocity components in a complete 3D laser-illuminated measurement volume. This new experimental facility includes a three-camera linear array of Imager Pro 5 cameras with Scheimpflug lens arrangements to keep the measurement volume in focus and is capable of time-series flow measurements at up to 14 Hz with capabilities to capture image pairs up to ~50 ns apart. This facility is located in 413 Libermann Hall, in Duquesne University (Pittsburgh, PA), and was set up in November 2015.
The experimental focus & future trajectory of this lab is illustrated as a word-cloud below:
The experimental focus & future trajectory of this lab is illustrated as a word-cloud below:
Surgical planning and Interventional Guidance
Multi-modal image fusion for real-time therapeutic guidance
Mastery over the art of fusing extra-operative ECHO, SPECT, MRI or data any other functional imaging modality onto a structural shell (from CT or MR); including: ECHO-CT, SPECT-CT fusion and MR-CT fusion. Fiducial registration and/or shape-based registration is employed to translate these objective physics-based renderings into the operative space, having full compatibility with commercial surgical navigation platforms.
Diagnostics: Pre-operative Evaluation &
Post-operative Monitoring of Cardiac BioMechanics
Novel analytics in objective cardiologist friendly forms
Planning open-heart surgeries conducted in India at Dr.Devi Shetty’s Narayana Hrudayalaya Hospital, with Dr.P.V.Rao and Dr.Srilaksmi M Adhyapak, for surgical ventricular restoration (SVR) in heart-failure patients with ventricular aneurysms.
...with great success!
12 Patients and counting - software-as-a-service (SaaS) image analytics for pre-surgical planning and post-operative monitoring of SVR.
Mechanical dyssynchrony, torsion mechanics and flow - all in one place.
Wall motion characterization by shape analysis
Personalized hemodynamics evaluation &
pre-surgical planning
In future, personalized open-heart cardiovascular procedure planning will include 3D morphometry as an input for surgical choice followed by evaluation of vascular reconstruction options using high-performance direct numerical simulation (DNS) computational fluid dynamics (CFD)...
Tetralogy of Fallot, Fontan, Cerebral Aneurysms, Aortic Aneurysms, Coarctation of Aorta ... the list goes on; the MeDCaVE has been involved with a series of published personalized clinical cases and specialized cohort research studies for pre-operative planning, post-surgical evaluation, and optimal blood handling device use strategy in pediatric and adult cardiovascular procedures. In one example, our pre-operative planning strategy for Tetralogy of Fallot based on our peer-reviewed / presented studies at the ASME and BMES annual meetings (2013), is described pictorially below:
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NIH funded:
Geometric Surrogates for Clinical Management of Abdominal Aortic Aneurysms:
26 March 2015: National Institutes of Health (NIH) R01 proposal titled, "Geometric Surrogates for Clinical Management of Abdominal Aortic Aneurysms", involving intimate collaboration with The MeDCaVE, awarded $1.7 Million over 5 years, starting in April 2015, through University of Texas at San Antonio (UTSA PI: Dr. Ender Finol; Co-investigators: Drs. P.G. Menon & S. Avril (Mines-Saint-Etienne)).
This grant award supports clinical research on abdominal aortic aneurysm (AAA) rupture risk prediction. The main goal of the study is to identify the patient-specific AAA geometry characteristics that are surrogates for patient-specific peak wall rupture risk index.
This study also received an American Heart Association (AHA) Pre-Doctoral Fellowship award funded for 2 years, starting 1 July 2015, to Mirunalini Thirugnanasambandam, PhD candidate at UTSA. Dr. Menon serves as a consultant on her AHA pre-doctoral award and also serves as a PhD thesis committee member.
This grant award supports clinical research on abdominal aortic aneurysm (AAA) rupture risk prediction. The main goal of the study is to identify the patient-specific AAA geometry characteristics that are surrogates for patient-specific peak wall rupture risk index.
This study also received an American Heart Association (AHA) Pre-Doctoral Fellowship award funded for 2 years, starting 1 July 2015, to Mirunalini Thirugnanasambandam, PhD candidate at UTSA. Dr. Menon serves as a consultant on her AHA pre-doctoral award and also serves as a PhD thesis committee member.
Noninvasive scalp detection of cortical spreading depression for brain injury:
October 2015: CerebroScope (www.cerebro-scope.com) - a medical device startup in the traumatic brain injury diagnostics space, collaborating with The MeDCaVE, for receiving a favorable SBIR Intent to Award! [PA14-071] - PHS 2014-02 omnibus solicitation of the NIH, CDC, FDA and ACF for small business innovation research grant applications (parent SBIR [R43/R44]) NIH appl. ID: 9047941]. Dr. Menon is a co-founder and principal of CerebroScope (SciencePlusPlease LLC).
October 2015: CerebroScope (www.cerebro-scope.com) - a medical device startup in the traumatic brain injury diagnostics space, collaborating with The MeDCaVE, for receiving a favorable SBIR Intent to Award! [PA14-071] - PHS 2014-02 omnibus solicitation of the NIH, CDC, FDA and ACF for small business innovation research grant applications (parent SBIR [R43/R44]) NIH appl. ID: 9047941]. Dr. Menon is a co-founder and principal of CerebroScope (SciencePlusPlease LLC).
Non- NIH:
This project was funded by the CMU-SYSU Collaborative Innovation Research Center (CIRC) for the 2014-2015 period. This project in collaboration with CMU Silicon Valley seeks to leverage Big Data and cloud computing techniques for the purpose of improving patient-specific medical care. Through improved Big Data machine learning techniques founded on parallel and distributed computing, this proposal aims at facilitating cloud based medical device design and optimization to better inform personalized device usage. To review the progress on this grant as well as related publications presented at the latest CIRC Review meeting, click here.
3D Printing as a Pre-Surgical Planning Tool for Personalized Therapy.
This work is sponsored by the 2016 Faculty Development Fund (FDF 2016) grant award from Duquesne University to Dr. Menon. During the performance period of this award, 3D printing will be investigated as a tactile tool to enhance the pre-surgical planning experience for minimally invasive left-atrial appendage occlusion procedures as well as for practicing open-heart surgical strategy for cardiac myectomy in patient with hypertrophic cardiomyopathy. The FDF award funds this project between August 2016 to August 2018.
Pre-Clinical Readiness Testing of Breast Palpation Aid for Home and Primary Care
This project was funded by the Disruptive Health Technology Institute (DHTI) and the Institute for Complex Engineered Systems (ICES) is part of the Carnegie Institute of Technology (CIT), at Carnegie Mellon University. This project in collaboration with Prof. James F. Antaki from Carnegie Mellon University's Biomedical Engineering Department. The objective of this proposal is to equip the primary care physicians with a sensitive visualization tool to detect and track the size, shape, stiffness and location of a palpable breast mass, to screen for breast cancer lesions.
This project was funded by the Disruptive Health Technology Institute (DHTI) and the Institute for Complex Engineered Systems (ICES) is part of the Carnegie Institute of Technology (CIT), at Carnegie Mellon University. This project in collaboration with Prof. James F. Antaki from Carnegie Mellon University's Biomedical Engineering Department. The objective of this proposal is to equip the primary care physicians with a sensitive visualization tool to detect and track the size, shape, stiffness and location of a palpable breast mass, to screen for breast cancer lesions.
4D Analysis of PatelloFemoral Pain Syndrome using MRI-based virtual Motion Analysis of the knee joint
This project in collaboration with South Africa's Stellenbosch University (Dr Cobus Muller), addresses the issue of the subjective nature of evaluating joint pain and the complications of intra-subject variability to design efficacious intervention protocols for patients with patellofemoral pain syndrome. It is imperative to evaluate patellofemoral pain syndrome on a patient-specific basis using advance imaging and image processing technology which reveals the interaction between bone and cartilagenous structures of the knee. A continuum shape-based patellofemoral motion analysis paradigm is investigated by The MeDCaVE to characterize pain during functional movement.
Peer-Reviewed PUBLICATIONS
[updated 12-29-2019]
Peer-reviewed publications in 2019 :
[1] Balaji Rengarajan, Wei Wu, Crystal Wiedner, Daijin Ko, Satish C. Muluk, Mark K. Eskandari, Prahlad G. Menon & Ender A. Finol . A Comparative Classification Analysis of Abdominal Aortic Aneurysms by Machine Learning Algorithms. Ann Biomed Eng (2020). https://doi.org/10.1007/s10439-020-02461-9
[2] Lee, A., Landau, R., Lavin, T., Goodman, S., Menon, P. and Smiley, R., 2019. Comparative efficacy of epidural clonidine versus epidural fentanyl for treating breakthrough pain during labor: a randomized double-blind clinical trial. International Journal of Obstetric Anesthesia.
[3] Jones, S.C., Gopalakrishna, P.M., Kharlamov, A., Sauter, P.M., Alba, N.A., Hund, S.J. and Singer, E., Scienceplusplease dba Cerebroscope LLC, 2019. Non-invasive Systems and Methods to Detect Cortical Spreading Depression for the Detection and Assessment of Brain Injury and Concussion. U.S. Patent Application 16/041,763.
Peer-reviewed publications in 2018 :
[1] Sanatkhani, S., Shroff, S.G., Menon, P.G., "Thrombus Risk Prediction in Atrial Fibrillation: Hemodynamic Model of Left Atrial Appendage" (2018). AHA Scientific Sessions, Chicago, IL, 10-12 November 2018.
[2] S Sanatkhani, M Oladosu, K Chera, S Nedios, PG Menon, "Relating regional characteristics of left atrial shape to presence of scar in patients with atrial fibrillation", SPIE Medical Imaging 2018: Image Processing 10574, 105742N 2018
[3] S Sanatkhani, PG Menon, "Generative statistical modeling of left atrial appendage appearance to substantiate clinical paradigms for stroke risk stratification", SPIE Medical Imaging 2018: Image Processing 10574, 105742L
[4] Sanatkhani, S., Menon, P.G., Shroff, S.G. and Nedios, S., 2018. Thrombus Risk Prediction in Atrial Fibrillation: Hemodynamic Model of Left Atrial Appendage. Circulation, 138(Suppl_1), pp.A11255-A11255.
[5] Morgan, J.J., Wilson, O.C. and Menon, P.G., 2018, November. The Wisdom of Crowds Approach to Influenza-Rate Forecasting. In ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers Digital Collection.
[6] Sanatkhani, S. and Menon, P.G., 2018, November. Three-Dimensional Cephalometric Analysis Using Computed Tomographic Imaging. In ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers Digital Collection.
[7] Valen-Sendstad, Kristian, et al. "Real-world variability in the prediction of intracranial aneurysm wall shear stress: The 2015 International Aneurysm CFD Challenge." Cardiovascular engineering and technology 9.4 (2018): 544-564.
Peer-reviewed publications in 2017 :
[1] Sanatkhani, S.**, Menon, P.G., 2017. Relating Atrial Appendage Flow Stasis Risk from Computational Fluid Dynamics to Imaging Based Appearance Paradigms for Cardioembolic Risk. Lecture Notes in Computer Science 10549, 86–93. DOI: 10.1007/978-3-319-67552-7_11 .
[2] Sanatkhani, S.** and Menon, P.G., 2017, Imaging based Left Atrial Appendage Shape Classification for Stasis Risk Stratification. Biomedical Engineering Society (BMES), Phoenix, AZ, 11-14 October 2017. (Poster Presentation)
[3] Sanatkhani, S.**, Shroff, S.G. and Menon, P.G., 2017, Personalized Design and Virtual Evaluation of Physician-Modified Stent Grafts for Juxta-Renal Abdominal Aortic Aneurysms. In SPIE Medical Imaging (pp. 101332C-101332C). International Society for Optics and Photonics.
[4] Soroosh Sanatkhani**, Marissa Finoli, Sanjeev Shroff, Prahlad G. Menon, 2017, "Visualization of Patient-Specific Hemodynamics in Atrial Fibrillation Using Computational and Experimental Models." 5th International Conference on Computational and Mathematical Biomedical Engineering – CMBE 2017, 10-12 April 2017, United States.
[5] Srilakshmi M. Adhyapak, Prahlad G. Menon, V. Rao Parachuri; Improvements in left ventricular twist mechanics following myectomy for hypertrophic cardiomyopathy with mid-ventricular obstruction. Interact CardioVasc Thorac Surg 2017 ivx054. doi: 10.1093/icvts/ivx054
[6] Eric Lambert, Prahlad G Menon, Tristan Ford, Satya VVN Kothapalli, Hong Chen and Jelena M. Janjic, Balancing colloidal stability and stimulus-responsiveness in a perfluorocarbon nanoemulsion platform for on demand drug delivery. 2017 World Molecular Imaging Congress, 13-16 Sept 2017, Philadelphia, PA [Poster Presentation]
[7] Michael Oladosu***, Karandeep Chera***, Soroosh Sanatkhani**, Prahlad Menon (2017) "Medical image segmentation, geometry preparation and 3D printing for in-vitro flow visualization in patient-specific left atrial geometries", in 2017 Summer Undergraduate Research Symposium, Duquesne University.
Peer-reviewed publications in 2016 :
[1] Rochon, E.R., Menon, P.G. and Roman, B.L., 2016. Alk1 controls arterial endothelial cell migration in lumenized vessels. Development, pp.dev-135392.
[2] Menon, P.G., Adhyapak, S.M. and Varghese, K., 2016, November. Regional Vascular Characterization of Ectatic Coronary Arteries From Fluoroscopy. In ASME 2016 International Mechanical Engineering Congress and Exposition (pp. V003T04A016-V003T04A016). American Society of Mechanical Engineers.
[3] Zahnd, E., Movahedi, F., Coyle, J.L., Sejdić, E. and Menon, P.G., 2016, November. Correlating Tri-Accelerometer Swallowing Vibrations and Hyoid Bone Movement in Patients With Dysphagia. In ASME 2016 International Mechanical Engineering Congress and Exposition (pp. V003T04A083-V003T04A083). American Society of Mechanical Engineers.
[4] Prahlad G. Menon, Srilakshmi M Adhyapak, V Rao Parachuri, Ou Yuanchang, Richard Weeks. "Virtual Surgical Myectomy as a Planning Tool for Obstructive Hypertrophic Cardiomyopathy." Society for Cardiovascular Magnetic Resonance (SCMR) Annual Scientific Sessions, Los Angeles, CA (27-30 January 2016). Journal of Cardiovascular Magnetic Resonance 2016, 18(Suppl 1):P46.
[5] Prahlad G. Menon, Sotirios Nedios, Gerhard Hindricks, Andreas Bollmann. "Investigating relationships between left atrial volume, symmetry, and sphericity." Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97882J (March 29, 2016); doi:10.1117/12.2216491. Presented at SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. Paper No. MI102-213.
[6] Yaoxiu Hu**, Prahlad G. Menon. "A neural network approach to lung nodule segmentation." Proc. SPIE 9784, Medical Imaging 2016: Image Processing, 97842O (March 21, 2016); doi:10.1117/12.2217291. Presented at SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. Paper No. MI102-349.
[7] Prahlad G. Menon, Elizabeth R. Rochon, Beth L. Roman. "In-vivo cell tracking to quantify endothelial cell migration during zebrafish angiogenesis." Proc. SPIE 9784, Medical Imaging 2016: Image Processing, 97844A (March 21, 2016); doi:10.1117/12.2217614. Presented at SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. . Paper No. MI102-400.
[8] Mohammad Sulman Ali, Prahlad G. Menon, Gerhard Hindricks, Andreas Bollmann, Sotirios Nedios, "Regional Characterization of Left Atrial Shape in Atrial Fibrillation." BMES/FDA Frontiers in Medical Devices Conference scheduled for May 23-25, 2016 in College Park, Maryland.
[9] S. Nedios, P.G. Menon, T. Seewöster, A. Arya, P. Sommer, G. Hindricks, A. Bollmann. "Association of low-voltage areas (substrate) with the regional wall deformation and the left atrial shape in patients with atrial fibrillation." German Society Of Cardiology Fall Conference 2016 (DGK 2016), Berlin, Germany, 6-8 October 2016.
[10] C Benzinger, P.G. Menon, H. Hong. "Characterization of Optimal Strategy for Glenn Anastomosis using Statistical Shape Models." BMES 2016, Minneapolis, MN, 6 October 2016. (Poster Presentation).
Peer-reviewed publications in 2015 :
[1] Ludwig DR, Menon PG, Schwartzman D. Nuclear image-guided left ventricular pacing lead navigation feasibility of a new technique. J Interv Card Electrophysiol. 2015 Aug 30. PubMed PMID: 26319647.
[2] Yang Gao**, Yongjie (Jessica) Zhang , Prahlad G. Menon. "3D shape comparison of cardiac geometries using a Laplace spectral-shape-matching approach." Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization. DOI:10.1080/21681163.2015.1057867 .
[3] Gopalakrishnan, V., Menon, P. G., Madan, S. (2015). "cMRI-BED: A novel informatics framework for cardiac MRI biomarker extraction and discovery applied to pediatric cardiomyopathy classification." BioMedical Engineering OnLine 2015, 14(Suppl 2):S7. DOI:10.1186/1475-925X-14-S2-S7.
[4] Ludwig, D. R., Menon, P. G., Fill, B., Gartner, M., & Schwartzman, D. (2015). "A Novel Toolkit to Improve Percutaneous Subxiphoid Needle Access to the Healthy Pericardial Sac." Journal of Cardiovascular Electrophysiology, 26(5), 576-580.
[5] Ludwig, D. R., Menon, P. G., & Schwartzman, D. (2015). "CT-Electromagnetic Three-Dimensional Tracking for Renal Endovascular Sympathetic Ablation Catheter Positioning in an Animal Model." J Vasc Interv Radiol. 2015 Jan 27. pii: S1051-0443(14)01151-8. doi: 10.1016/j.jvir.2014.11.025. PubMed PMID: 25636671.
[6] Menon, P.G., Adhypak, S.M., Williams, R.B., Doyle, M., Biederman, R.W.W.. "Investigating Cardiac MRI Based Right Ventricular Contractility As A Novel Non-Invasive Metric of Pulmonary Arterial Pressure." Clin Med Insights Cardiol. 2014; 8(Suppl 1): 45–50.
[7] Menon, P.G., Katz, W., Schwartzman, D. "Quantitative Biomarkers of Left Atrial Appendage Morphology & Function for Stroke Risk Stratification in Patients with Atrial Fibrillation." AHA Fellows Research Day 2015, Pittsburgh, PA. 23 January 2015.
[8] Menon, P.G., Hong, H. "Interactive pre-surgical design of optimal extra-cardiac Fontan connections starting with cardiac MRI reconstructions of the Glenn anastomosis." Journal of Cardiovascular Magnetic Resonance 2015, 17(Suppl 1):P197, SCMR/Euro CMR Joint Scientific Sessions, Nice, France. February 5-7, 2015. (Poster Presentation)
[9] Menon, P.G., Hong, H. "Evaluating MRI based vascular wall motion as a biomarker of Fontan hemodynamic performance." SPIE Medical Imaging Symposium. Orlando, FL. 21 - 26 February 2015. (Poster Presentation)
[10] Mirunalini Thirugnanasambandam**, Prahlad G. Menon, Stephane Avril, Ender A. Finol, "Novel image-based analysis of patient-specific abdominal aortic aneurysm wall stress using a membrane mechanics model." 2015 Summer Biomechanics, Bioengineering and BIotransport Conference (SB3C), June 17-20, 2015, Utah. (Oral Presentation)
[11] Jiexin Guo**, Prahlad G Menon, "Feature based classification of melanoma from skin images." ASME 2015 International Mechanical Engineering Congress & Exposition, November 13-19, 2015, Houston, Texas. (Oral Presentation)
[12] Deanna C. Easley*, Prahlad G. Menon, Pamela M. Moalli, Steven D. Abramowitch, "Inter-observer variability of vaginal wall segmentation from MRI: a statistical shape analysis approach." ASME 2015 International Mechanical Engineering Congress & Exposition, November 13-19, 2015, Houston, Texas. (Oral Presentation)
[13] Pedro Antonio Nájera-Olvera**, Prahlad G Menon, "Automatic identification of genu valgum from tibio-femoral short radiographs." ASME 2015 International Mechanical Engineering Congress & Exposition, November 13-19, 2015, Houston, Texas. (Oral Presentation)
[14] Yuanyuan Ma**, Prahlad G Menon, "Automatic Tracking and Classification of Time-resolved Facial Expressions from Images." BMES Annual Meeting, Tampa, FL. October 7-10, 2015. (Poster Presentation
[15] Yaoxiu Hu**, Prahlad G Menon, "Neural Network approach for Lung Nodule Segmentation." BMES Annual Meeting, Tampa, FL. October 7-10, 2015. (Poster Presentation)
[16] M. Alperin, S. D. Abramowitch, D. Easley**, P. G. Menon, M. S. Cook, W. Barone (2015). “A Novel Approach to Map Quantified Fascicle Data onto a 3D Model of Pelvic Floor Muscles.” American Urogynecologic Society (AUGS) 36th Annual Scientific Meeting Tuesday, October 13 - Saturday, October 17, 2015. Seattle, WA (CONTROL ID: 2281303. Oral Presentation).
[17] Philipp Berg, Christoph Roloff, Oliver Beuing, Samuel Voss, Shin-Ichiro Sugiyama, Nicolas Aristokleous, Andreas S. Anayiotos, Neil Ashton, Alistair Revell, Neil W. Bressloff, Alistair G. Brown, Bong Jae Chung, Juan R. Cebral, Gabriele Copelli, Wenyu Fu, Aike Qiao, Arjan J. Geers, Simona Hodis, Dan Dragomir-Daescu, Emily Nordahl, Yildirim Bora Suzen, Muhammad Owais Khan, Kristian Valen-Sendstad, Kenichi Kono, Prahlad G. Menon, Priti G. Albal**, Otto Mierka, Raphael Münster, Hernán G. Morales, Odile Bonnefous, Jan Osman, Leonid Goubergrits, Jordi Pallares, Salvatore Cito, Alberto Passalacqua, Senol Piskin, Kerem Pekkan, Susana Ramalho, Nelson Marques, Stéphane Sanchi, Kristopher R. Schumacher, Jess Sturgeon, Helena Švihlová, Jaroslav Hron, Gabriel Usera, Mariana Mendina, Jianping Xiang, Hui Meng, David A. Steinman and Gábor Janiga. The Computational Fluid Dynamics Rupture Challenge 2013-Phase II: Variability of Hemodynamic Simulations in Two Intracranial Aneurysms. Journal of Biomechanical Engineering. doi:10.1115/1.4031794
[18] Prahlad G. Menon, Sotirios Nedios, Gerhard Hindricks, Andreas Bollmann. "Investigating relationships between left atrial volume, symmetry, and sphericity." SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. Paper No. MI102-213.
[19] Yaoxiu Hu**, Prahlad G. Menon. "A neural network approach to lung nodule segmentation." SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. Paper No. MI102-349.
[20] Prahlad G. Menon, Elizabeth R. Rochon, Beth L. Roman. "In-vivo cell tracking to quantify endothelial cell migration during zebrafish angiogenesis." SPIE Medical Imaging, San Diego, CA. 27 February - 3 March 2016. . Paper No. MI102-400.
[21] Easley, D.C., Menon, P.G., Rostaminia, G., Shobeiri, S.A., Abramowitch, S.D. Impact of Endovaginal Ultrasound on the Anatomical Positioning of Pelvic Floor Organs. Pittsburgh MR Imaging Community Retreat, Pittsburgh, PA, November 5, 2015 (Poster)
[22] Rostaminia, G., Easley, D.C., Menon, P.G., Shobeiri, S.A., Abramowitch, S.D. Is the Pelvic Floor Anatomy Distorted During Pelvic Floor Endovaginal Ultrasound? 36th American Urogynecology Society Annual Scientific Meeting, Seattle, WA, October 13-17, 2015 (Oral Presentation)
Peer-reviewed publications in 2014 :
[1] Rao, A. S.***, Menon, P. G. (2014). "Pre-surgical planning using image-based in-silico anatomical and functional characterization of Tetralogy of Fallot with associated anomalies." Interactive Cardiovascular and Thoracic Surgery, ivu368. DOI: 10.1093/icvts/ivu368
[2] Menon, P.G., Ludwig, D., Lacomis, J., Schwartzman, D., Toma, C., 2014. "Computed Tomographic Analysis of Left Ventricular Volumes and Function after Implantation of the Parachute® Endoventricular Partitioning Device." Journal of Interventional Cardiology. DOI: 10.1111/joic.12151.
[3] Adhyapak, S. M.*, Menon, P. G.* & Rao Parachuri, V., Gadabanahalli, K, Bhat, V. R, Shetty V. and Shetty, D. (2014). “Restoration of optimal left ventricular apical geometry and rotation following surgical ventricular restoration using rectangular patch plasty technique: a pilot study using cardiac magnetic resonance.” Interactive cardiovascular and thoracic surgery, ivu173. DOI: 10.1093/icvts/ivu173. [* -- joint first authors]
[4] Adhyapak, S. M.*, Menon, P. G.* & Rao Parachuri, V. (2014). “Characterization of dysfunctional remote myocardium in left ventricular anterior aneurysms and improvements following surgical ventricular restoration using cardiac magnetic resonance imaging-preliminary results.” Interactive cardiovascular and thoracic surgery, ivu162. DOI: 10.1093/icvts/ivu162 [* -- joint first authors]
[5] Kruzick, S., Mengshoel, O., Menon, P. G. (2014). “Detection of Myocardial Perfusion Defects Using First Pass Perfusion CMR Data.” Springer, Lecture Notes in Computer Science). DOI10.1007/978-3-319-09994-1_23 .
[6] Piao, D., Menon, P. G., Mengshoel, O. (2014). “Computing Probabilistic Optical Flow using Markov Random Fields.” Springer, Lecture Notes in Computer Science). DOI: 10.1007/978-3-319-09994-1_22.
[7] Menon, P. G., Adhyapak, S. M. & Rao Parachuri, V. (2014). “Analysis of cardiac MRI based regional timing of left ventricular mechanical contraction as a biomarker for electrical dyssynchrony in heart-failure 9atients.” Springer, Lecture Notes in Computer Science (LNCS). DOI: 10.1007/978-3-319-09994-1_5 .
[8] Menon, P. G.*, Muller, J. H.* (2014). “Characterization of a novel imaging based metric of patello-femoral separation using computational modeling.” Springer, Lecture Notes in Computer Science). DOI: 10.1007/978-3-319-09994-1_17 . [* -- joint first authors]
[9] Gao, Y., Liao, T., Zhang, Y., Menon, P. G. (2014). “Development of active shape models for left ventricular function in ischemic cardiomyopathy.” Paper accepted for publication in the proceedings of CompIMAGE 2014 (to appear in Springer, Lecture Notes in Computer Science), Sept 3-5, 2014.
[10] S.M Adhyapak*, P.G Menon*, A Mehra***, S Tully, V Rao Parachuri, "Rapid quantification of mean myocardial wall velocity in ischemic cardiomyopathy by cardiac magnetic resonance: An index of cardiac functional abnormalities during the cardiac cycle." Journal of Clinical and Experimental Cardiology. Accepted on 21 February 2014. [* -- joint first authors]
[11] S.M Adhyapak*, P.G Menon*, V Rao Parachuri, " Pre-surgical planning and optimization of surgical techniques of surgical ventricular restoration by in-silico simulations." Asian Cardiovascular and Thoracic Annals. Accepted on 14 February 2014. [*-- joint first authors] DOI: 10.1177/0218492314528341.
[12] Friehling, M, P.G Menon, D R Ludwig, D Schwartzman, "SPECT-CT Fusion Image Integration to Support Left Ventricular Substrate Ablation.” The European Journal of Pacing, Arrhythmias and Cardiac Electrophysiology (Case Report, EP-Europace, DOI: 10.1093/europace/euu073).
[13] P.G Menon, A Mehra***, M Doyle, R W W Biederman, E Finol, “Rapid 4D regional wall motion characterization of abdominal aortic aneurysms with intra-luminal thrombus using cine cardiac MRI.” Journal of Cardiovascular Magnetic Resonance 2014, 16(Suppl 1):P385. doi:10.1186/1532-429X-16-S1-P385. Presented at the Society for Cardiovascular Magnetic Resonance (SCMR) 17th Annual Scientific Sessions, New Orleans, LA. 16-19 January 2014. Control ID: 1806186. (Poster Presentation)
[14] P.G Albal**, T Montidoro, O Dur, P.G Menon ,"Patient-Specific Hemodynamic evaluation of an Aortic Coarctation under Rest and Stress conditions." Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. Springer Berlin Heidelberg, 2014. 83-93. DOI: 10.1007/978-3-642-54268-8_10.
[15] P.G Menon, A.S Rao***, P.G Albal**, "Surgical planning using in-silico anatomical and functional characterization of Tetralogy of Fallot with associated anomalies." Society of Thoracic Surgeons 50th Annual Meeting, January 25-29, 2014, Orlando, FL. (Oral Presentation)
[16] P.G Menon, S.M Adhyapak, Parachuri, V Rao, "Regional mean myocardial velocity of remote myocardium following surgical ventricular restoration in heart failure patients with anterior aneurysms: An index of improved post-operative left ventricular performance." AHA Fellows Research Day 2014 Pittsburgh, PA. February 14, 2014.
[17] Prahlad G. Menon, Lailonny Morris, Mara Staines, Joao Lima, Daniel C. Lee, Colin Lee, Vanathi Gopalakrishnan, “Novel MRI-derived quantitative biomarker for cardiac function applied to classifying ischemic cardiomyopathy within a Baysian rule learning framework.” SPIE Medical Imaging Symposium. 18 February 2014, San Diego, CA. DOI: 10.1117/12.2042118.
[18] V Gopalakrishnan, P. G Menon, S Madan, “A novel framework to enhance scientific knowledge of cardiovascular MRI biomarkers and their application to pediatric cardiomyopathy classification.” IWBBIO 2014 (2nd International Work-Conference on Bioinformatics and Biomedical Engineering), Granada, Spain. April 7-9, 2014.
[19] J.F Antaki, A Daly, M Jamiolkowski, M.V Kameneva, M Massoudi, A Martin, P.G Menon, W.R Wagner, W-T Wu, “Trafficking of Platelets and Red Blood Cells: Theoretical and Experimental.” 7th World Congress of Biomechanics, Boston, MA. July 6-11, 2014.
[20] P.G. Menon, P.G. Albal, "In-silico evaluation of effects of swirl direction and intensity on aortic flow patterns induced by an aortic pump using computational fluid dynamics." ASME 2014 International Mechanical Engineering Congress & Exposition. Nov 14-20, 2014 [IMECE2014-39711]. (Oral Presentation). DOI:10.1115/IMECE2014-39711
[21] P.G. Menon, A.S. Rao, "4D mitral valve motion analysis using multi-plane cine cardiac MRI reconstructions for functional classification of patients with mitral regurgitation." ASME 2014 International Mechanical Engineering Congress & Exposition. Nov 14-20, 2014 [IMECE2014-39910]. (Oral Presentation). DOI:10.1115/IMECE2014-39910
[22] Prahlad G. Menon, Priti G. Albal, Brian A. Mosier, Lance Maynard, John Christoforetti, "Regional characterization of effective joint space & hip-joint capsule volume from magnetic resonance imaging." BMES Annual Meeting, San Antonio, TX. October 22-25, 2014. (Poster Presentation)
[23] Lindsey SE, Menon PG, Kowalski WJ, Shekhar A, Yalcin HC, Nishimura N, Schaffer CB, Butcher JT, Pekkan K. Growth and hemodynamics after early embryonic aortic arch occlusion. Biomech Model Mechanobiol. 2014 Nov 23. PubMed PMID: 25416845.
Peer-reviewed publications in 2013:
[1] S.M Adhyapak*, P.G Menon*, V Rao Parachuri, "Restoration of optimal ellipsoid left ventricular geometry – lessons learned from in-silico surgical modeling." Journal of Interactive CardioVascular Thoracic Surgery (ICVTS). Accepted on 20 September 2013. DOI: 10.1093/icvts/ivt464 [*-- joint first authors]
[2] Kowalski, W.J, N.C.Teslovich, P.G.Menon, J.P.Tinney, B.B.Keller, K.Pekkan, " Left atrial ligation alters intracardiac flow patterns and the biomechanical landscape in the chick embryo." Journal of Developmental Dynamics. DOI: 10.1002/dvdy.24107
[3] Yueh-Hsun Lu, Chia-Yuan Chen, Prahlad G. Menon, Kuan-Ting Liu, Hsing-Hung Lin, "Hemodynamic effects of endoleak formation in abdominal aortic aneurysm patients with stent-graft implants." Journal of Medical and Biological Engineering, In Press Uncorrected Proof, Available online 15 Oct 2013. DOI: 10.5405/jmbe.1588
[4] Chen, C.-Y., Antón, R., Hung, M.-Y., Menon, P. G., Patrick, M. J., Finol, E. A., and Pekkan, K., 2014, “Effects of intraluminal thrombus on patient-specific abdominal aortic aneurysm hemodynamics via stereoscopic PIV and CFD modeling," Journal of Biomechanical Engineering-Transactions of the ASME. doi: 10.1115/1.4026160.
[5] P.G Albal**, P.G Menon ," MRI & CT image-fusion based aorta & coronary artery model for in-silico feasibility evaluation of perfusion with an ascending aortic pump, using computational fluid dynamics." Journal of Medical Devices. Presented at ASME/FDA 1st Annual Frontiers in Medical Devices, Applications of Computer Modeling and Simulation (ASME FMD 2013). (Oral presentation & published paper) DOI: 10.1115/1.4025630
[6] P.G Menon, S.M Adhyapak,V Rao Parachuri, "Quantitative analysis of regional morphology and mechanical dyssynchrony using cardiac MRI for optimal surgical ventricular restoration." AHA Scientific Sessions, Dallas, Texas, November 17, 2013, Poster Presentation. (Conference Proceedings Publication).
[7] Prahlad G. Menon*, Haifa Hong*, Haibo Zhang, Hucheng Li, Zhongqun Zhu Huiwen Chen, Jinfen Liu, "Post surgical comparison of pulsatile hemodynamics in five unique Fontan connections – identifying an ideal connection strategy." Annals of Thoracic Surgery, 2013. 10.1016/j.athoracsur.2013.05.035
[8] P.G Menon, J.F Antaki, A Undar, K Pekkan,"Aortic outflow cannula tip design and orientation impacts cerebral perfusion during pediatric cardiopulmonary bypass procedures." Annals of Biomedical Engineering, journal of the Biomedical Engineering Society, 2013. DOI: 10.1007/s10439-013-0857-8.
[9] Menon, P.G, R.W.W Biederman, "Automated 3D morphometric difference biomarker for abnormal ventricular morphology." Journal of Cardiovascular Magnetic Resonance, 2013. 15(Suppl 1):E35.
E-poster presentation at Society for Cardiovascular Magnetic Resonance (SCMR) 16th Annual Scientific Sessions, San Francisco, CA. 30 January - 3 February 2013.
[10] D R Ludwig, P.G Menon, M Friehling, D Schwartzman, "Feasibility of SPECT-CT Guided Left Ventricular Lead Deployment for Cardiac Resynchronization Therapy." Journal of Nuclear Cardiology, 2013. Presented at annual meeting of American Society of Nuclear Cardiology (ASNC), September 26–29, 2013, Chicago, IL. (Poster Presentation)
[11] P.G Menon, S.M Adhyapak,"Cardiac MRI based in-silico quantitative comparison of morphology and mechanics after surgical ventricular restoration by the Dor procedure vs. linear endoventricular patch-plasty." BMES 2013 annual meeting, September 25-28, 2013. Seattle, Washington. (Poster Presentation).
[12] M.Eckman***, P.G Menon ," 4D shape analysis applied to post-operative wall motion function assessment of extracardiac total cavopulmonary connections." BMES 2013 annual meeting, September 25-28, 2013. Seattle, Washington. (Oral Presentation).
[13] A.Mehra***, S.Tully, S.M.Adhyapak, P.G Menon ," Quantification of cardiac function by shape analysis for early diagnosis of ventricular remodeling, from 4-D cardiac MRI." BMES 2013 annual meeting, September 25-28, 2013, Seattle, Washington. (Poster Presentation).
[14] P.G Albal**, T Montidoro, O Dur, P.G Menon ,"Patient-Specific Hemodynamic evaluation of an Aortic Coarctation under Rest and Stress conditions." 2013 International Workshop on Statistical Atlases and Computational Models of the Heart at the 16th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), Nagoya, Japan. 26 September 2013. (E-poster presentation. Published in Springer LNCS. DOI: 10.1007/978-3-642-54268-8_10). This paper won the The MeDCaVE the best paper award at STACOM 2013, Nagoya, Japan.
[15] P.G Albal**, P.G Menon, "In-silico mechanical analysis and feasibility study on the InSitu-Lok – a flexible external tubing connector for extracorporeal circuitry." BMES 2013 annual meeting, September 25-28, 2013. (Poster Presentation)
[16] A.S Rao***, P.G Menon, "Morphological characterization to inform complex surgical decisions in chronic Tetralogy of Fallot." BMES 2013 annual meeting, September 25-28, 2013. (Oral Presentation)
[17] A.S Rao***, P.G Albal, P.G Menon, "Patient-specific hemodynamic evaluation and in-silico surgical planning for optimal interventions in Tetralogy of Fallot patients." ASME 2013 International Mechanical Engineering Congress & Exposition, November 15-21, 2013, San Diego, CA. (Poster Presentation)
[18] P.G Menon, W.J Kowalski, K Pekkan, "Computational fluid dynamics analysis of early embryonic aortic arch-ligation." Accepted for presentation and published in proceedings of ASME Summer Bioengineering Conference, June 26-29, 2013, Sunriver, Oregon (Poster Presentation)
[19] P.G Menon, S.M Adhyapak, "Shape Analysis for Automatic and Objective Visualization of Pathological Cardiovascular Remodeling from Cine Cardiac MRI." Accepted for presentation and published in proceedings of ASME Summer Bioengineering Conference, June 26-29, 2013, Sunriver, Oregon. [Summary: Demonstration of two shape analysis techniques based on spherical harmonics (SPHARM) and Hausdorff distance, to analyze ventricular function in a patient with a post-infarct ventricular aneurysm. (Poster Presentation)
[20] P.G Menon, V Rao Parachuri, S.M Adhyapak, "Quantitative analysis of regional function and mechanical dyssynchrony using CMR for patients with post-infarction left ventricular remodeling." AHA Fellows Research Day 2013. February 15, 2013. [Summary: We sought to first characterize basal and apical rotation in a 7 patients with post-infarction antero-apical aneurysms and secondly to study whether the extent of LV remodeling, characterized by regional LV volumes (RLVV), was related to severity of mechanical dyssynchrony in these patients.] (Poster Presentation)
[21] Yoshida, M, P.G Menon, C Chrysostomou, K Pekkan, P Wearden, Jacqueline Kreutzer, Vivekanand Allada, V Morell, "右室流出路導管の術後流出路形状の評価とそれにあわせてデザインされたPTFE 弁付き導管の早期成績: Early clinical results of specially designed valved polytetrafluoroethyleme conduit for right ventricular outflow." 66th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery. 16-19 October 2013, Sendai, Japan.
[22] Kerem Pekkan, PhD, Berk Yigit, Prahlad G Menon, Senol Piskin, William Kowalski, Ahmet Sasmazel, MD , "Impact of Integrated Computational Fluid Dynamics and Lumped Parameter Modeling on Neonatal CPB and Congenital Heart Surgery." Artif Organs, Vol. 37, No. 4, 2013.
2012 and earlier publications are listed at www.linkedin.com/in/prahladmenon
[*- joint first authors, ** - MS/PhD student with The MeDCaVE, *** - Student researcher with The MeDCaVE & QuantMD intern.]
[2] Menon, P.G., Ludwig, D., Lacomis, J., Schwartzman, D., Toma, C., 2014. "Computed Tomographic Analysis of Left Ventricular Volumes and Function after Implantation of the Parachute® Endoventricular Partitioning Device." Journal of Interventional Cardiology. DOI: 10.1111/joic.12151.
[3] Adhyapak, S. M.*, Menon, P. G.* & Rao Parachuri, V., Gadabanahalli, K, Bhat, V. R, Shetty V. and Shetty, D. (2014). “Restoration of optimal left ventricular apical geometry and rotation following surgical ventricular restoration using rectangular patch plasty technique: a pilot study using cardiac magnetic resonance.” Interactive cardiovascular and thoracic surgery, ivu173. DOI: 10.1093/icvts/ivu173. [* -- joint first authors]
[4] Adhyapak, S. M.*, Menon, P. G.* & Rao Parachuri, V. (2014). “Characterization of dysfunctional remote myocardium in left ventricular anterior aneurysms and improvements following surgical ventricular restoration using cardiac magnetic resonance imaging-preliminary results.” Interactive cardiovascular and thoracic surgery, ivu162. DOI: 10.1093/icvts/ivu162 [* -- joint first authors]
[5] Kruzick, S., Mengshoel, O., Menon, P. G. (2014). “Detection of Myocardial Perfusion Defects Using First Pass Perfusion CMR Data.” Springer, Lecture Notes in Computer Science). DOI10.1007/978-3-319-09994-1_23 .
[6] Piao, D., Menon, P. G., Mengshoel, O. (2014). “Computing Probabilistic Optical Flow using Markov Random Fields.” Springer, Lecture Notes in Computer Science). DOI: 10.1007/978-3-319-09994-1_22.
[7] Menon, P. G., Adhyapak, S. M. & Rao Parachuri, V. (2014). “Analysis of cardiac MRI based regional timing of left ventricular mechanical contraction as a biomarker for electrical dyssynchrony in heart-failure 9atients.” Springer, Lecture Notes in Computer Science (LNCS). DOI: 10.1007/978-3-319-09994-1_5 .
[8] Menon, P. G.*, Muller, J. H.* (2014). “Characterization of a novel imaging based metric of patello-femoral separation using computational modeling.” Springer, Lecture Notes in Computer Science). DOI: 10.1007/978-3-319-09994-1_17 . [* -- joint first authors]
[9] Gao, Y., Liao, T., Zhang, Y., Menon, P. G. (2014). “Development of active shape models for left ventricular function in ischemic cardiomyopathy.” Paper accepted for publication in the proceedings of CompIMAGE 2014 (to appear in Springer, Lecture Notes in Computer Science), Sept 3-5, 2014.
[10] S.M Adhyapak*, P.G Menon*, A Mehra***, S Tully, V Rao Parachuri, "Rapid quantification of mean myocardial wall velocity in ischemic cardiomyopathy by cardiac magnetic resonance: An index of cardiac functional abnormalities during the cardiac cycle." Journal of Clinical and Experimental Cardiology. Accepted on 21 February 2014. [* -- joint first authors]
[11] S.M Adhyapak*, P.G Menon*, V Rao Parachuri, " Pre-surgical planning and optimization of surgical techniques of surgical ventricular restoration by in-silico simulations." Asian Cardiovascular and Thoracic Annals. Accepted on 14 February 2014. [*-- joint first authors] DOI: 10.1177/0218492314528341.
[12] Friehling, M, P.G Menon, D R Ludwig, D Schwartzman, "SPECT-CT Fusion Image Integration to Support Left Ventricular Substrate Ablation.” The European Journal of Pacing, Arrhythmias and Cardiac Electrophysiology (Case Report, EP-Europace, DOI: 10.1093/europace/euu073).
[13] P.G Menon, A Mehra***, M Doyle, R W W Biederman, E Finol, “Rapid 4D regional wall motion characterization of abdominal aortic aneurysms with intra-luminal thrombus using cine cardiac MRI.” Journal of Cardiovascular Magnetic Resonance 2014, 16(Suppl 1):P385. doi:10.1186/1532-429X-16-S1-P385. Presented at the Society for Cardiovascular Magnetic Resonance (SCMR) 17th Annual Scientific Sessions, New Orleans, LA. 16-19 January 2014. Control ID: 1806186. (Poster Presentation)
[14] P.G Albal**, T Montidoro, O Dur, P.G Menon ,"Patient-Specific Hemodynamic evaluation of an Aortic Coarctation under Rest and Stress conditions." Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. Springer Berlin Heidelberg, 2014. 83-93. DOI: 10.1007/978-3-642-54268-8_10.
[15] P.G Menon, A.S Rao***, P.G Albal**, "Surgical planning using in-silico anatomical and functional characterization of Tetralogy of Fallot with associated anomalies." Society of Thoracic Surgeons 50th Annual Meeting, January 25-29, 2014, Orlando, FL. (Oral Presentation)
[16] P.G Menon, S.M Adhyapak, Parachuri, V Rao, "Regional mean myocardial velocity of remote myocardium following surgical ventricular restoration in heart failure patients with anterior aneurysms: An index of improved post-operative left ventricular performance." AHA Fellows Research Day 2014 Pittsburgh, PA. February 14, 2014.
[17] Prahlad G. Menon, Lailonny Morris, Mara Staines, Joao Lima, Daniel C. Lee, Colin Lee, Vanathi Gopalakrishnan, “Novel MRI-derived quantitative biomarker for cardiac function applied to classifying ischemic cardiomyopathy within a Baysian rule learning framework.” SPIE Medical Imaging Symposium. 18 February 2014, San Diego, CA. DOI: 10.1117/12.2042118.
[18] V Gopalakrishnan, P. G Menon, S Madan, “A novel framework to enhance scientific knowledge of cardiovascular MRI biomarkers and their application to pediatric cardiomyopathy classification.” IWBBIO 2014 (2nd International Work-Conference on Bioinformatics and Biomedical Engineering), Granada, Spain. April 7-9, 2014.
[19] J.F Antaki, A Daly, M Jamiolkowski, M.V Kameneva, M Massoudi, A Martin, P.G Menon, W.R Wagner, W-T Wu, “Trafficking of Platelets and Red Blood Cells: Theoretical and Experimental.” 7th World Congress of Biomechanics, Boston, MA. July 6-11, 2014.
[20] P.G. Menon, P.G. Albal, "In-silico evaluation of effects of swirl direction and intensity on aortic flow patterns induced by an aortic pump using computational fluid dynamics." ASME 2014 International Mechanical Engineering Congress & Exposition. Nov 14-20, 2014 [IMECE2014-39711]. (Oral Presentation). DOI:10.1115/IMECE2014-39711
[21] P.G. Menon, A.S. Rao, "4D mitral valve motion analysis using multi-plane cine cardiac MRI reconstructions for functional classification of patients with mitral regurgitation." ASME 2014 International Mechanical Engineering Congress & Exposition. Nov 14-20, 2014 [IMECE2014-39910]. (Oral Presentation). DOI:10.1115/IMECE2014-39910
[22] Prahlad G. Menon, Priti G. Albal, Brian A. Mosier, Lance Maynard, John Christoforetti, "Regional characterization of effective joint space & hip-joint capsule volume from magnetic resonance imaging." BMES Annual Meeting, San Antonio, TX. October 22-25, 2014. (Poster Presentation)
[23] Lindsey SE, Menon PG, Kowalski WJ, Shekhar A, Yalcin HC, Nishimura N, Schaffer CB, Butcher JT, Pekkan K. Growth and hemodynamics after early embryonic aortic arch occlusion. Biomech Model Mechanobiol. 2014 Nov 23. PubMed PMID: 25416845.
Peer-reviewed publications in 2013:
[1] S.M Adhyapak*, P.G Menon*, V Rao Parachuri, "Restoration of optimal ellipsoid left ventricular geometry – lessons learned from in-silico surgical modeling." Journal of Interactive CardioVascular Thoracic Surgery (ICVTS). Accepted on 20 September 2013. DOI: 10.1093/icvts/ivt464 [*-- joint first authors]
[2] Kowalski, W.J, N.C.Teslovich, P.G.Menon, J.P.Tinney, B.B.Keller, K.Pekkan, " Left atrial ligation alters intracardiac flow patterns and the biomechanical landscape in the chick embryo." Journal of Developmental Dynamics. DOI: 10.1002/dvdy.24107
[3] Yueh-Hsun Lu, Chia-Yuan Chen, Prahlad G. Menon, Kuan-Ting Liu, Hsing-Hung Lin, "Hemodynamic effects of endoleak formation in abdominal aortic aneurysm patients with stent-graft implants." Journal of Medical and Biological Engineering, In Press Uncorrected Proof, Available online 15 Oct 2013. DOI: 10.5405/jmbe.1588
[4] Chen, C.-Y., Antón, R., Hung, M.-Y., Menon, P. G., Patrick, M. J., Finol, E. A., and Pekkan, K., 2014, “Effects of intraluminal thrombus on patient-specific abdominal aortic aneurysm hemodynamics via stereoscopic PIV and CFD modeling," Journal of Biomechanical Engineering-Transactions of the ASME. doi: 10.1115/1.4026160.
[5] P.G Albal**, P.G Menon ," MRI & CT image-fusion based aorta & coronary artery model for in-silico feasibility evaluation of perfusion with an ascending aortic pump, using computational fluid dynamics." Journal of Medical Devices. Presented at ASME/FDA 1st Annual Frontiers in Medical Devices, Applications of Computer Modeling and Simulation (ASME FMD 2013). (Oral presentation & published paper) DOI: 10.1115/1.4025630
[6] P.G Menon, S.M Adhyapak,V Rao Parachuri, "Quantitative analysis of regional morphology and mechanical dyssynchrony using cardiac MRI for optimal surgical ventricular restoration." AHA Scientific Sessions, Dallas, Texas, November 17, 2013, Poster Presentation. (Conference Proceedings Publication).
[7] Prahlad G. Menon*, Haifa Hong*, Haibo Zhang, Hucheng Li, Zhongqun Zhu Huiwen Chen, Jinfen Liu, "Post surgical comparison of pulsatile hemodynamics in five unique Fontan connections – identifying an ideal connection strategy." Annals of Thoracic Surgery, 2013. 10.1016/j.athoracsur.2013.05.035
[8] P.G Menon, J.F Antaki, A Undar, K Pekkan,"Aortic outflow cannula tip design and orientation impacts cerebral perfusion during pediatric cardiopulmonary bypass procedures." Annals of Biomedical Engineering, journal of the Biomedical Engineering Society, 2013. DOI: 10.1007/s10439-013-0857-8.
[9] Menon, P.G, R.W.W Biederman, "Automated 3D morphometric difference biomarker for abnormal ventricular morphology." Journal of Cardiovascular Magnetic Resonance, 2013. 15(Suppl 1):E35.
E-poster presentation at Society for Cardiovascular Magnetic Resonance (SCMR) 16th Annual Scientific Sessions, San Francisco, CA. 30 January - 3 February 2013.
[10] D R Ludwig, P.G Menon, M Friehling, D Schwartzman, "Feasibility of SPECT-CT Guided Left Ventricular Lead Deployment for Cardiac Resynchronization Therapy." Journal of Nuclear Cardiology, 2013. Presented at annual meeting of American Society of Nuclear Cardiology (ASNC), September 26–29, 2013, Chicago, IL. (Poster Presentation)
[11] P.G Menon, S.M Adhyapak,"Cardiac MRI based in-silico quantitative comparison of morphology and mechanics after surgical ventricular restoration by the Dor procedure vs. linear endoventricular patch-plasty." BMES 2013 annual meeting, September 25-28, 2013. Seattle, Washington. (Poster Presentation).
[12] M.Eckman***, P.G Menon ," 4D shape analysis applied to post-operative wall motion function assessment of extracardiac total cavopulmonary connections." BMES 2013 annual meeting, September 25-28, 2013. Seattle, Washington. (Oral Presentation).
[13] A.Mehra***, S.Tully, S.M.Adhyapak, P.G Menon ," Quantification of cardiac function by shape analysis for early diagnosis of ventricular remodeling, from 4-D cardiac MRI." BMES 2013 annual meeting, September 25-28, 2013, Seattle, Washington. (Poster Presentation).
[14] P.G Albal**, T Montidoro, O Dur, P.G Menon ,"Patient-Specific Hemodynamic evaluation of an Aortic Coarctation under Rest and Stress conditions." 2013 International Workshop on Statistical Atlases and Computational Models of the Heart at the 16th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), Nagoya, Japan. 26 September 2013. (E-poster presentation. Published in Springer LNCS. DOI: 10.1007/978-3-642-54268-8_10). This paper won the The MeDCaVE the best paper award at STACOM 2013, Nagoya, Japan.
[15] P.G Albal**, P.G Menon, "In-silico mechanical analysis and feasibility study on the InSitu-Lok – a flexible external tubing connector for extracorporeal circuitry." BMES 2013 annual meeting, September 25-28, 2013. (Poster Presentation)
[16] A.S Rao***, P.G Menon, "Morphological characterization to inform complex surgical decisions in chronic Tetralogy of Fallot." BMES 2013 annual meeting, September 25-28, 2013. (Oral Presentation)
[17] A.S Rao***, P.G Albal, P.G Menon, "Patient-specific hemodynamic evaluation and in-silico surgical planning for optimal interventions in Tetralogy of Fallot patients." ASME 2013 International Mechanical Engineering Congress & Exposition, November 15-21, 2013, San Diego, CA. (Poster Presentation)
[18] P.G Menon, W.J Kowalski, K Pekkan, "Computational fluid dynamics analysis of early embryonic aortic arch-ligation." Accepted for presentation and published in proceedings of ASME Summer Bioengineering Conference, June 26-29, 2013, Sunriver, Oregon (Poster Presentation)
[19] P.G Menon, S.M Adhyapak, "Shape Analysis for Automatic and Objective Visualization of Pathological Cardiovascular Remodeling from Cine Cardiac MRI." Accepted for presentation and published in proceedings of ASME Summer Bioengineering Conference, June 26-29, 2013, Sunriver, Oregon. [Summary: Demonstration of two shape analysis techniques based on spherical harmonics (SPHARM) and Hausdorff distance, to analyze ventricular function in a patient with a post-infarct ventricular aneurysm. (Poster Presentation)
[20] P.G Menon, V Rao Parachuri, S.M Adhyapak, "Quantitative analysis of regional function and mechanical dyssynchrony using CMR for patients with post-infarction left ventricular remodeling." AHA Fellows Research Day 2013. February 15, 2013. [Summary: We sought to first characterize basal and apical rotation in a 7 patients with post-infarction antero-apical aneurysms and secondly to study whether the extent of LV remodeling, characterized by regional LV volumes (RLVV), was related to severity of mechanical dyssynchrony in these patients.] (Poster Presentation)
[21] Yoshida, M, P.G Menon, C Chrysostomou, K Pekkan, P Wearden, Jacqueline Kreutzer, Vivekanand Allada, V Morell, "右室流出路導管の術後流出路形状の評価とそれにあわせてデザインされたPTFE 弁付き導管の早期成績: Early clinical results of specially designed valved polytetrafluoroethyleme conduit for right ventricular outflow." 66th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery. 16-19 October 2013, Sendai, Japan.
[22] Kerem Pekkan, PhD, Berk Yigit, Prahlad G Menon, Senol Piskin, William Kowalski, Ahmet Sasmazel, MD , "Impact of Integrated Computational Fluid Dynamics and Lumped Parameter Modeling on Neonatal CPB and Congenital Heart Surgery." Artif Organs, Vol. 37, No. 4, 2013.
2012 and earlier publications are listed at www.linkedin.com/in/prahladmenon
[*- joint first authors, ** - MS/PhD student with The MeDCaVE, *** - Student researcher with The MeDCaVE & QuantMD intern.]
The MeDCaVE epitomizes patient specific medical diagnostics at the confluence of Physics and quantitative image analysis ...
Learn more about The MeDCaVE's and QuantMD's expertise amplification strategy for remote networked workflow, EASY-RENEWTM , here or experience it for yourself by playing with the aorta model built for in-silico testing of our published feasibility study on intra-aortic axial flow blood pumps!
